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Uses

This combination medication is used to deal with signs of Parkinson's disease or symptoms that are parkinson-likesuch as shakiness, stiffness, difficulty moving). Parkinson's disease is thought to be caused by too little of a substance that is naturally occurringdopamine) into the brain. Levodopa modifications into dopamine in mental performance, helping to control movement. Carbidopa prevents the breakdown of levodopa in the bloodstream so more levodopa can enter mental performance. Carbidopa can also reduce some of levodopa's side effects such as for instance vomiting and nausea.

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How to use Sinemet

Take this medication by lips with or without food as directed by the doctor, frequently 3 to 4 times a day.

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Taking this medication with meals might help to decrease nausea. It is best to avoid a high-protein diet (it decreases the quantity of levodopa that your particular body takes in) during treatment, unless directed otherwise by the doctor. Separate your dose of the medication by since hours that are many possible from any iron supplements or products containing iron (such as multivitamins with minerals) you may take. Iron can reduce the amount of this medication absorbed by the body. Consult your pharmacist or doctor for more details.

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The dosage relies on your medical condition and response to treatment. To reduce your risk of adverse effects, your doctor may direct you to start this medication at a dose that is low gradually increase your dose. Follow your doctor's instructions carefully. This combination medication comes in different strengths with different amounts of carbidopa and levodopa in each tablet. Be sure you have the strength that is correct of drugs. Your doctor might also prescribe carbidopa alone to be studied with this combination.

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Use this medication regularly to get the benefit that is most from it. To help you remember, take it at the same times each day.

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Some clients may experience a "wearing-off" (worsening of symptoms) ahead of the next dose is due. An "on-off" effect may also happen, in which unexpected short periods of stiffness occur. If these effects occur, contact your doctor for feasible dosage adjustments that will help to reduce this effect.

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Do not stop taking this medication without consulting your medical professional. Some conditions could become even worse whenever this drug is quickly reduced or suddenly stopped. Your dose may need to be gradually reduced. (See also Side Effects section.)

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Tell your medical practitioner in the event your condition does not improve or if it worsens.

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adverse Impacts

Dizziness, lightheadedness, nausea, vomiting, loss of appetite, difficulty sleeping, uncommon dreams, or headache may take place. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

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This medication may cause saliva, urine, or perspiration to turn a color that is dark. This impact is harmless, your clothes might be stained.

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To cut back the possibility of dizziness and lightheadedness, get fully up slowly whenever increasing from a sitting or position that is lying.

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Remember that your doctor has prescribed this medication she has judged that the benefit to you is greater than the risk of adverse effects because he or. Many people using this medication do not have serious side effects.

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Some individuals taking this medication have dropped asleep abruptly throughout their usual daily activities (such as talking on the phone, driving). In some full cases, rest occurred without any emotions of drowsiness upfront. This sleep effect may occur anytime during therapy with carbidopa/levodopa no matter if you used this medication for a long time. Until you have discussed this effect with your doctor if you experience increased sleepiness or fall asleep during the day, do not drive or do other possibly dangerous activities. Your risk of this sleep impact is increased by using alcohol or other medicines that will allow you to drowsy. See also Precautions section.

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Tell your doctor right away you can't control/spasms, greatly increased eye blinking/twitching, fainting, vision changes (such as blurred vision, double vision), eye pain, severe stomach/abdominal pain, black/tarry stools, vomit that looks like coffee grounds, mental/mood changes (such as agitation, hallucinations, depression, thoughts of suicide), signs of infection (such as sore throat that doesn't go away), easy bleeding/bruising, unusual tiredness, tingling of the hands/feet, unusual strong urges (such as increased gambling, increased sexual urges) if you have any serious adverse effects, including: new/worsening movements.

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Get medical help right away if you have actually any very severe side results, including: upper body pain.

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Abruptly stopping or reducing the dose with this medicine may hardly ever cause a very condition that is serious neuroleptic malignant syndrome (NMS). Get medical help right away for those who have any of the following symptoms: fever, unusual muscle tightness, serious confusion, perspiring, fast/irregular heartbeat, quick breathing.

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an extremely serious allergic reaction to this drug is rare. However, get help that is medical away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially associated with face/tongue/throat), serious dizziness, trouble respiration.

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This is not a complete list of possible adverse effects. If you notice other effects not listed above, contact your pharmacist or doctor.

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Call your medical professional for medical advice about side-effects. You could report side effects to Food And Drug Administration at 1-800-FDA-1088 or at www.fda.gov/medwatch.

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In Canada - Phone your doctor for medical advice about part effects. You may report effects that are side Health Canada at 1-866-234-2345.

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Precautions

Before using this medicine, tell your doctor or pharmacist if you are allergic to carbidopa or levodopa; or if you have any other allergies. This product may contain ingredients that are inactive which can cause allergy symptoms or other problems. Keep in touch with your pharmacist for lots more details.

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Before applying this medicine, tell your doctor or pharmacist your health background, especially of: liver disease, glaucoma, breathing issues (such as for instance asthma), heart disease (such as for example heart attack, irregular heartbeat), kidney illness, stomach/intestinal ulcer, mental/mood disorders (such as depression, schizophrenia), blood problems, seizures, sleep disorders.

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This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness you can perform such activities safely until you are sure. Limit alcoholic beverages. See also adverse Effects section.

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Before having surgery, tell your doctor or dentist about all of the products you utilize (including prescription drugs, nonprescription drugs, and organic products).

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During pregnancy, this medication should be utilized only once plainly needed. Discuss the potential risks and benefits with your physician.

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Levodopa passes into breast milk. Its unknown if carbidopa passes into breast milk. Consult with your physician before breast-feeding.

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