Methotrexate can be used to treat certain forms of cancer or to control psoriasis that is severe rheumatoid arthritis that has not responded to other treatments. It may also be used to control juvenile rheumatoid arthritis. Methotrexate belongs to a class of drugs known as antimetabolites. It works by slowing or stopping the development of cancer cells and suppressing the immune system.
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Early treatment of rheumatoid arthritis symptoms with more aggressive treatment such as for example methotrexate assists to lessen further joint damage and to preserve function that is joint.
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OTHER USES: This section contains uses of this drug which are not listed in the approved labeling that is professional the drug but that may be prescribed by the health care expert. Make use of this medication for a state of being which is listed in this part only if it offers been so prescribed by your health care professional.
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This medication may also be used for lupus and arthritis that is psoriatic.
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Read the Patient Information Leaflet if available from your pharmacist before you start taking methotrexate and each time you get a refill. If you have any relevant questions, ask your doctor or pharmacist.
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Methotrexate is a medication that is strong. The dosage and how often you take this medication are based on your condition that is medical and to therapy. There are many different dosing schedules for this medication (especially for cancer therapy). Therefore, it is crucial that you follow your physician's directions carefully. Take this medication by mouth as directed by your doctor.
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For the treatment of psoriasis or arthritis rheumatoid, just take this medicine by mouth as directed by your medical professional, often as soon as a week. It might take around a few months before you get the benefit that is full of drug.
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Don't increase your dose or use this drug more often or for longer than prescribed. Your condition shall not improve any faster, along with your risk of negative effects will increase.
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Since this medication may be consumed through the skin and lung area and may also harm an unborn baby, women who are pregnant or who may become pregnant must not handle this medication or breathe the dirt through the pills.
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Drink plenty of liquids while taking this medication unless your physician informs you otherwise. Doing so assists your kidneys to remove the drug from the body and give a wide berth to a few of the relative negative effects.
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Nausea, vomiting, stomach pain, drowsiness, or dizziness may occur. If any of these effects persist or worsen, tell your pharmacist or doctor quickly.
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Temporary hair loss might occur. Normal hair regrowth should return after treatment has ended.
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Remember that the physician has recommended this medicine she has judged that the benefit to you is greater than the risk of side effects because he or. Many people using this medication do not have serious side effects.
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Tell your physician appropriate away if you have any adverse that is serious, including: mouth sores, diarrhea, signs of anemia (such as for instance unusual tiredness, pale skin), signs of liver issues (such as dark urine, persistent nausea/vomiting, stomach/abdominal pain, yellowing eyes/skin), easy bruising/bleeding, black stools, enlarged glands/lymph nodes, bone tissue pain, unusual discomfort and discoloration of skin, modification in the amount of urine, dry cough, muscle weakness.
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Get medical help right away if you have got any very serious side-effects, including: weakness on one side of the body, throat stiffness, serious frustration, eyesight changes, irregular heartbeat, mental/mood changes, seizures.
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This medication might lower your ability to fight infections. This may make you more likely to get a serious (rarely fatal) infection or make any infection you have worse. Tell your doctor right away if you have any signs of infection (such as fever, chills, persistent sore throat, cough).
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This medicine can affect sperm production, an impact that may lower fertility that is male. Consult with your doctor for lots more details.
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A very severe reaction that is allergic this drug is rare. However, get help that is medical away if you notice any observeable symptoms of a serious hypersensitive reaction, including: rash, itching/swelling (especially for the face/tongue/throat), severe dizziness, difficulty breathing.
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It is not a list that is complete of side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
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Call your medical professional for medical advice about negative effects. You may possibly report effects that are side FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
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In Canada - Call your doctor for medical advice about adverse effects. You may report side effects to wellness Canada at 1-866-234-2345.
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Before taking methotrexate, inform your medical professional or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain ingredients that are inactive that may cause allergic responses or other problems. Talk to your pharmacist for additional information.
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Before using this medication, tell your doctor or pharmacist your medical background, especially of: liver condition, renal disease, lung disease (such as for example pulmonary fibrosis), liquor usage, suppressed immune system, blood cell/bone marrow disorders, stomach/intestinal diseases (such as peptic ulcer, ulcerative colitis), any active illness (including chickenpox or recent exposure to it), folic acid deficiency.
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Methotrexate will make you more likely to get infections or may worsen any infections that are current. Consequently, wash the hands well to avoid the spread of infection. Avoid contact with people who have infections that may spread to other people (such as chickenpox, measles, flu). Consult your physician for those who have been subjected to an infection or for more details.
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Don't have immunizations/vaccinations without the consent of your physician. Prevent contact with those who have recently received live vaccines (such as for example flu vaccine inhaled through the nose).
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To lower the chance of getting cut, bruised, or injured, use caution with sharp objects like razors and nail cutters, and steer clear of activities such as for example contact sports.
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This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Avoid alcoholic beverages.
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Before having surgery, tell your doctor or dental practitioner about all the products you use (including prescription drugs, nonprescription medications, and herbal products).
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This medicine may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear clothing that is protective outdoors.
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Methotrexate must not be used during pregnancy. It might harm an unborn baby. It is important to prevent pregnancy during and after treatment with methotrexate. Therefore, males and females must use reliable forms of birth control (such as condoms, birth control pills) during treatment. Males should continue to use birth control for at least 3 months after the final end of treatment. Females should continue to use contraception for at least 1 menstrual cycle after the end of treatment. If you become pregnant or think you may be pregnant, tell your doctor right away.
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Since this drug can be absorbed through the skin and lungs and may harm an baby that is unborn women who are pregnant or who may become pregnant should not manage this medicine or breathe the dust from the tablets.
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Methotrexate passes into breast milk and may harm a nursing infant. Therefore, breast-feeding while using the this drug isn't recommended. Consult with your medical practitioner before breast-feeding.
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