See section that is also warning.
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This medicine is used to treat mental/mood that is certain (schizophrenia, schizoaffective disorders). Clozapine is a medication that is psychiatricanti-psychotic type) that works by assisting to restore the balance of particular normal substances (neurotransmitters) into the brain.
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Clozapine decreases hallucinations and aids in preventing committing suicide in individuals who are likely to use to harm on their own. It helps you to definitely clearly think more and absolutely about your self, feel less nervous, and be a part of everyday life.
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If you are utilising the liquid form of this medication, read the Patient Suggestions Leaflet if available from your pharmacist before you start taking clozapine and every time you get a refill. For those who have any relevant questions, pose a question to your doctor or pharmacist.
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Just take this medicine by mouth with or without food, as directed by your doctor. If you are taking the pills that dissolve in the mouth, carefully remove each tablet from the blister pack immediately before taking your dose. Allow the tablets to dissolve on your tongue and swallow. There is no need to take the dissolving tablets with water. Discard any dissolving tablets that are previously confronted with air due to opened/damaged packaging. Do not save them for your next dose.
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If you work with the form that is liquid of medication, shake the bottle well for 10 seconds before each use. Carefully measure the dose using a special measuring device/spoon. Don't use a household spoon because you might not get the dose that is correct.
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It is critical to begin taking this drug at a dose that is low increasing your dose slowly, to lessen side effects such as dizziness, drowsiness and seizures. Follow your doctor's instructions exactly. Your dosage is based on your condition that is medical and to treatment. Since clozapine can cause a decrease in white blood cells, you will need certainly to get blood tests done regularly as directed. Be sure to keep all appointments of these laboratory tests. (See also Notes section.)
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If you miss your doses for longer than a day or two, consult your doctor for a new schedule to get back to the dose you were on (see Missed Dose section). Use this medication regularly in order to get the most benefit from this. To simply help you remember, utilize it at the same time(s) each day.
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Do not stop clozapine that is taking consulting your doctor. Some conditions may become worse when the drug is suddenly stopped. Also, you might experience symptoms such as severe sweating, headache, nausea, vomiting, and diarrhea. To avoid these symptoms while you're stopping therapy with this medication, your medical professional may lower your dosage slowly. Check with your doctor or pharmacist for more details. Report any new or symptoms that are worsening away.
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It might take weeks ahead of the full benefit of this medication takes effect. Inform your physician if for example the condition persists or worsens.
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Drooling, drowsiness, dizziness, headache, shaking tremor that is(, vision problems (e.g., blurred vision), weight gain, and constipation may occur. Many of these effects (especially drowsiness) lessen as your body gets used to the medication. If any of these effects persist or worsen, contact your doctor or pharmacist quickly.
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To stop constipation, maintain a meal plan adequate in fiber, drink plenty of water, and exercise. If you become constipated while using this drug, consult your pharmacist for help in selecting a laxative (age.g., stimulant-type with stool softener).
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Understand that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of adverse effects. Many people using this medication do not have serious adverse effects.
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This medication may make your blood rarely sugar level rise, which can cause or worsen diabetes. Rarely, very serious conditions such as diabetic coma may occur. Tell your physician straight away if you develop symptoms of high blood sugar levels, such as increased thirst and urination. If you already have diabetic issues, make sure to always check your blood sugars regularly. Your doctor might need to adjust your diabetes medication, exercise program, or diet.
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This medication may also cause weight that is significant and a rise in your cholesterol (or triglyceride) levels. These effects, along with diabetes, may increase your risk for developing heart disease. Discuss the risks and advantages of treatment with your doctor.
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Tell your physician right away when you yourself have any serious adverse effects, including: facial/muscle twitching, seizures, uncontrollable movements.
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Get medical help right away if you have any very severe part effects, including: severe dizziness, fainting, mental/mood changes, difficulty respiration with workout, sudden weakness, pain/redness/swelling of the arms/legs, persistent nausea/vomiting, stomach/abdominal pain, yellowing of eyes/skin.
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This medication may rarely cause a really condition that is serious neuroleptic malignant syndrome (NMS). Get help that is medical away if you have any of the following symptoms: temperature, muscle tissue stiffness/pain/tenderness/weakness, serious tiredness, severe confusion, sweating, fast/irregular heartbeat, dark urine, improvement in the level of urine.
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A really severe allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may add: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
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This is simply not a list that is complete of side effects. If you notice other effects not listed above, contact your pharmacist or doctor.
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Call your medical practitioner for medical advice about part results. You may report effects that are side FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
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In Canada - Call your doctor for medical advice about side effects. You'll report adverse effects to Health Canada at 1-866-234-2345.
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Before using clozapine, inform your medical practitioner or pharmacist in the event that you are allergic to it or if you have any other allergies. This product may contain ingredients that are inactive which causes allergic reactions or other dilemmas. Confer with your pharmacist for more information.
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Before using this medication, tell your physician or pharmacist your medical history, particularly of: history of bloodstream disorders (such as for instance leukemia, low white blood cell count), bowel problems (such as paralytic ileus, cranky bowel syndrome ), difficulty in breathing, diabetes/family history of diabetes, high cholesterol/triglyceride levels, glaucoma, heart problems, kidney problems, liver problems, obesity/family history of obesity, seizures, difficulty urinating (such as prostate problems).
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Clozapine may cause a condition that impacts the center rhythm (QT prolongation). QT prolongation can rarely cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as for example serious dizziness, fainting) that need medical attention appropriate away.
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The possibility of QT prolongation may be increased if you have specific conditions that are medical are taking other drugs that may impact the heart rhythm. Before making use of clozapine, tell your physician or pharmacist of all the drugs you take and when you yourself have some of the following conditions: certain heart issues (heart failure, slow heartbeat, QT prolongation into the EKG), family history of certain heart problems (QT prolongation in the EKG, unexpected cardiac death).
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Low levels of potassium or magnesium in the blood may increase your risk also of QT prolongation. This risk may increase if you use certain drugs (such as diuretics/"water pills") or if you have conditions such as severe sweating, diarrhea, or vomiting. Talk to your doctor about using clozapine safely.
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This drug can make you dizzy or drowsy or cause vision that is blurred. Do not drive, use machinery, or do any activity that requires alertness or clear vision you can perform such activities safely until you are sure. Limit beverages that are alcoholic.
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Tell your medical professional because you may be at a higher risk for a drop in your white blood cells if you are a descendent of Ashkenazi Jews.
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Before having surgery, tell your dentist or doctor that you're making use of this medication.
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Liquid products or tablets that are dissolving contain sugar and/or aspartame. Liquid products may contain alcohol also. Caution is encouraged you to limit/avoid these substances in your diet if you have diabetes, liver disease, phenylketonuria (PKU), or any other condition that requires. Ask your pharmacist or doctor about using this product safely.
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Older grownups may be more responsive to the relative part aftereffects of this medication, particularly constipation, dizziness, and QT prolongation (see above). Dizziness can raise the danger of falling.
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During pregnancy, this medicine should be used only when plainly needed. Babies born to moms who purchased this drug over the past 3 months of pregnancy may rarely develop symptoms including muscle stiffness or shakiness, drowsiness, feeding/breathing difficulties, or constant crying. If you notice any of these symptoms in your newborn especially during their month that is first the doctor right away.
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Since untreated mental/mood problems (such as schizophrenia, schizoaffective disorders) can be a serious condition, do not stop taking this medication unless directed by your doctor. You may be pregnant, immediately discuss with your doctor the benefits and risks of using this medication during pregnancy if you are planning pregnancy, become pregnant, or think.
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This medicine may pass into breast milk and have undesirable effects on a nursing infant. Breast feeding is not recommended while taking clozapine. Consult your physician before breast-feeding.
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