Clomipramine is used to deal with obsessive disorder that is compulsiveOCD). It helps decrease persistent/unwanted thoughts (obsessions), and it helps reduce the urge to perform duplicated tasks (compulsions such as hand-washing, counting, checking) that interfere with everyday living.
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This medication belongs to a class of medicines called antidepressants that are tricyclic. It works by restoring the balance of certain substances that are naturalserotonin, and others) in the mind.
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OTHER USES: This part contains uses of this drug being not placed in the approved labeling that is professional the drug but which may be prescribed by your health care professional. Use this medication for a condition that is listed in this area only if it is often so prescribed by the health care professional.
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This medication has also been utilized to treat depression, panic attacks, and ongoing pain.
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Read the Medication Guide available from your pharmacist. Check with your pharmacist or doctor if you have any concerns.
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Take this medication by mouth with or without meals as directed by your medical professional. To minimize side-effects such as stomach upset, clomipramine may be started at a low dose, given in several doses during the day with meals, and slowly increased as your body gets used to it. After you have reached the best dose for you, the total dose can be taken once daily, usually at bedtime to prevent daytime drowsiness or as directed by your doctor. Frequently, the dose that is daily maybe not be more than 250 milligrams for adults and 200 milligrams for kiddies and teenagers.
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Follow your physician's guidelines very carefully. Do not take just about medication or take it more frequently than prescribed. Your condition shall not improve any faster and your threat of adverse effects such as for instance seizures may be increased. Dosage is based on your condition that is medical and to therapy.
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Avoid eating drinking or grapefruit grapefruit juice while being treated with this medication unless your doctor instructs you otherwise. Grapefruit can increase the amount of certain medications in your bloodstream. Consult your pharmacist or doctor for more details.
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Make use of this medication regularly in purchase to get the benefit that is most from it. Continue to take it even if you feel well. To help you remember, use it at the time( that is same) each day.
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Don't suddenly stop taking this medication without consulting your physician. Some conditions may become even worse when the drug is suddenly stopped. You may possibly experience sweating, dizziness, sickness, vomiting, headache, or irritability if you instantly stop taking this drug. Your dose may gradually need to be decreased.
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It might just take 2 to 3 months or longer before the full effects of this medication are noticed. Inform your physician if for example the condition persists or if it worsens.
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See also Warning section.
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Dizziness, drowsiness, dry mouth, constipation, stomach upset, nausea, vomiting, changes in appetite/weight, flushing, sweating, tiredness and blurred vision may occur. Anxiety symptoms may temporarily aggravate when you first start clomipramine that is taking. If any of these effects persist or worsen, notify your doctor or pharmacist quickly.
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To ease mouth that is dry suck on (sugarless) hard candy or ice chips, chew (sugarless) gum, drink water or use a saliva substitute.
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To stop constipation, maintain a diet adequate in fiber, drink plenty of water, and workout. If you feel constipated while making use of this drug, consult with your pharmacist for assist in selecting a laxative (e.g., stimulant-type with stool softener).
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Keep in mind that your doctor has recommended this medication she has judged that the benefit to you is greater than the risk of adverse effects because he or. Many people using this medication do not have adverse that is serious.
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Tell your physician right away if some of these unlikely but serious adverse effects happen: mental/mood changes (e.g., confusion, despair, memory problems), enlarged/painful breasts, unwanted breast milk manufacturing, irregular/painful menstrual durations, muscle stiffness, ringing in the ears, sexual issues (e.g., decreased sexual ability, alterations in desire), shakiness (tremors), numbness/tingling regarding the hands/feet, trouble urinating.
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Tell your doctor right away if any of these rare but very serious side effects occur: easy bruising/bleeding, signs of infection (e.g., fever, persistent sore throat), unusual/uncontrolled movements (especially of this tongue/face/lips), serious stomach/abdominal pain, dark urine, yellowing of eyes/skin.
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This medication may increase serotonin and rarely cause an extremely serious condition called serotonin syndrome/toxicity. The risk increases you take if you are also taking other drugs that increase serotonin, so tell your doctor or pharmacist of all the drugs. Get medical help right away if you develop a number of the following symptoms: fast heartbeat, hallucinations, loss of coordination, severe dizziness, severe nausea/vomiting/diarrhea, twitching muscles, unexplained fever, unusual agitation/restlessness.
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Get medical help right away in the event that you have very severe side effects, including: black stools, chest discomfort, fainting, slow/fast/irregular heartbeat, seizures, vomit that looks like coffee grounds, eye pain/swelling/redness, vision modifications (such as seeing rainbows around lights through the night).
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A very severe allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious reaction that is allergic: rash, itching/swelling (especially for the face/tongue/throat), severe dizziness, trouble breathing.
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This is not a list that is complete of adverse effects. If you notice other effects not listed above, contact your doctor or pharmacist.
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Call your doctor for medical advice about adverse effects. You may report effects that are side FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
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In Canada - Call your physician for medical advice about side-effects. You'll report effects that are side Health Canada at 1-866-234-2345.
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Before taking clomipramine, tell your doctor or pharmacist if you have any other allergies if you are allergic to it; or to other tricyclic antidepressants (e.g., imipramine, nortriptyline); or. This product may contain ingredients that are inactive which can cause allergies or other dilemmas. Talk to your pharmacist for additional information.
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Before applying this medicine, tell your doctor or pharmacist your medical history, especially of: bloodstream problems (e.g., purpura, thrombocytopenia), breathing problems (age.g., asthma, chronic bronchitis), individual or genealogy of glaucoma (angle-closure type), eating disorders (age.g., bulimia), heart problems (e.g., arrhythmias, coronary artery disease, recent heart attack), intestinal dilemmas (e.g., chronic constipation, ileus), liver problems, kidney dilemmas, personal or family history of other mental/mood conditions (e.g., bipolar disorder, schizophrenia), history of hospitalization for a very severe a reaction to specific medicines (neuroleptic cancerous syndrome), heartburn/stomach acid in the esophagus (e.g., due to hiatal hernia), seizures, overactive thyroid (hyperthyroidism), trouble urinating (urinary retention, enlarged prostate), any condition that may raise your threat of seizures (e.g., alcohol/sedative dependency, usage of electroconvulsive treatment, brain injury/disease), specific kinds of tumors (e.g., pheochromocytoma, neuroblastoma).
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Clomipramine may cause an ailment that affects the heart rhythm (QT prolongation). QT prolongation can hardly ever cause severe (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that need medical help straight away.
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The threat of QT prolongation might be increased in the event that you have actually certain conditions that are medical are using other drugs that might cause QT prolongation. Before using clomipramine, inform your medical professional or pharmacist of all of the drugs you take of course you've got any of the following conditions: certain heart disease (heart failure, slow heartbeat, QT prolongation in the EKG), family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death).
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Lower levels of potassium or magnesium in the blood may increase your risk also of QT prolongation. This risk may increase if you have conditions such as severe sweating, diarrhea, or vomiting if you use certain drugs (such as diuretics/"water pills") or. Talk to your medical practitioner about using clomipramine safely.
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This drug could make you dizzy or drowsy or cause temporary blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision you can perform such activities safely until you are sure. Limit beverages that are alcoholic.
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To decrease dizziness and lightheadedness, get up slowly when increasing from a seated or position that is lying.
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Before having surgery, tell your dentist or doctor that you're taking this medication.
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Care is recommended when working with this medication in kids who participate in active activities since it may increase the possibility of heart problems. (See also the Warning section.)
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Older adults may be more delicate to your relative adverse effects of this drug, especially bleeding, confusion, dizziness, and QT prolongation (see above).
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This medication should be used only when plainly needed during pregnancy. Newborns exposed to clomipramine during pregnancy might experience withdrawal symptoms or unwanted effects. Inform your doctor right away if you notice jitteriness, shaking, feeding problems, fast breathing, or seizures in your newborn.
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Since untreated mental/mood problems (such as obsessive disorder that is compulsive depression, panic attack) can be a serious condition, do not stop taking this medication unless directed by your doctor. If you are planning pregnancy, become pregnant, or think you may be pregnant, immediately discuss with your doctor the benefits and risks of using this medication during pregnancy.
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This drug passes into breast milk and could have undesirable effects on a nursing infant. Check with your doctor before breast-feeding.
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